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ROCK1 anticorps (AA 1114-1126)

ROCK1 Reactivité: Humain, Souris, Rat, Singe, Boeuf (Vache), Roussette (Chauve-souris), Chien, Cheval WB Hôte: Souris Monoclonal 154C1465 unconjugated
N° du produit ABIN207918
  • Antigène Voir toutes ROCK1 Anticorps
    ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
    Épitope
    • 16
    • 16
    • 15
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1114-1126
    Reactivité
    Humain, Souris, Rat, Singe, Boeuf (Vache), Roussette (Chauve-souris), Chien, Cheval
    Hôte
    • 72
    • 9
    Souris
    Clonalité
    • 59
    • 22
    Monoclonal
    Conjugué
    • 40
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp ROCK1 est non-conjugé
    Application
    • 70
    • 27
    • 26
    • 20
    • 17
    • 15
    • 13
    • 13
    • 11
    • 8
    • 6
    • 2
    • 1
    Western Blotting (WB)
    Specificité
    This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.
    Homologie
    Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Bovine, Dog, Bat, Horse, Opossum, Platypus (100%) Rabbit (92%) Chicken (85%).
    Purification
    Protein G purified
    Immunogène
    This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to residues 1114-1126 GNLPESRIEGWLS of human ROCK-1. Immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Bovine, Dog, Bat, Horse, Opossum, Platypus (100%), Rabbit (92%), Chicken (85%).

    Type of Immunogen: Synthetic peptide
    Clone
    154C1465
    Isotype
    IgG
    Top Product
    Discover our top product ROCK1 Anticorps primaire
  • Indications d'application
    Approved: WB (1 - 2 μg/mL)

    Not recommended for: IHC-P
    Commentaires

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS, 0.2 % gelatin, 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Antigène
    ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
    Autre désignation
    Rho Kinase / ROCK1 (ROCK1 Produits)
    Synonymes
    anticorps LOC100229794, anticorps CG9774, anticorps DROK, anticorps DRhk, anticorps DRok, anticorps Dmel\\CG9774, anticorps Drok, anticorps ROCK, anticorps ROCK-1, anticorps ROCK1, anticorps ROK, anticorps ROKalpha/beta, anticorps Rhk, anticorps RhoK, anticorps Rock, anticorps Rok, anticorps dROK, anticorps dRok, anticorps drok, anticorps 1110055K06Rik, anticorps Rock-I, anticorps P160Rock, anticorps ROCK-I, anticorps P160ROCK, anticorps p160ROCK, anticorps Rho associated coiled-coil containing protein kinase 1, anticorps Rho kinase, anticorps Rho-associated coiled-coil containing protein kinase 1, anticorps Rho-associated, coiled-coil containing protein kinase 1, anticorps ROCK1, anticorps Rok, anticorps Rock1, anticorps rock1
    Sujet
    Name/Gene ID: ROCK1
    Subfamily: ROCK
    Family: Protein Kinase

    Synonyms: ROCK1, p160 Rho-associated kinase, p160ROCK, p160 ROCK-1, p160-ROCK, p160RhoK, Rho-associated kinase, RockI, Rok, Rok alpha, Rho-alpha kinase, p160 rho-kinase, Rho kinase, ROCK-I, Rokalpha
    ID gène
    6093
    UniProt
    Q13464
    Pathways
    Dynamique des Microtubules, Signalisation WNT, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling
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