MPL anticorps (AA 615-628)

N° du produit ABIN211285

Cet anticorps Lapin Polyclonal détecte spécifiquement MPL dans WB, IHC et IP. Il présente une réactivité envers Humain, Souris, Hamster et Singe.

Aperçu rapide pour MPL anticorps (AA 615-628) (ABIN211285)

Antigène: MPL (Myeloproliferative Leukemia Virus Oncogene (MPL))

Reactivité: Humain, Souris, Hamster, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MPL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-MPL anticorps

Épitope: AA 615-628

Specificité: Recognizes glycosylated and unglycosylated human TPO receptor/c-Mpl, Mr 70kD. Species cross-reactivity: mouse. Species sequence Homology: mouse - 100 % .

Homologie: Percent identity by BLAST analysis: Human, Monkey, Mouse, Hamster (100%) Elephant, Rabbit (93%) Panda, Bovine, Pig (86%).

Purification: Protein A purified

Immunogène: Synthetic peptide corresponding to amino acids 615-628 of human TPO (thrombopoietin) receptor [C-ANHSYLPLSYWQQP] (KLH-conjugated). Species sequence Homology: Mouse - 100%. Percent identity by BLAST analysis: Human, Monkey, Mouse, Hamster (100%), Elephant, Rabbit (93%), Panda, Bovine, Pig (86%).

Type of Immunogen: Synthetic peptide - KLH conjugated

Isotype: IgG

Information d'application

Indications d'application: Approved: IHC, IP, WB (0.25 - 1 μg/mL)

Usage: Suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation. Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunohistochemistry: Stains megakaryocytes in bone marrow biopsy sections. Immunoprecipitation: 5 μg immunoprecipitates TPO receptor from 500 μg of DAMI RIPA lysate.

Not recommended for: IHC-P

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.1 M Tris-glycine,  pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide, 30 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur MPL

Antigène: MPL (Myeloproliferative Leukemia Virus Oncogene (MPL))

Autre désignation: CD110 / MPL

Sujet: Name/Gene ID: MPL

Synonyms: MPL, CD110 antigen, C-MPL, CD110, MPLV, Proto-oncogene c-Mpl, TPOR, TPO-R, THCYT2, Thrombopoietin receptor

ID gène: 4352

UniProt: P40238

Pathways: Signalistation JAK/STAT