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DPP4 anticorps

L’anticorps Souris Monoclonal anti-DPP4 a été validé pour FACS, IHC, IP et IHC (fro). Il convient pour détecter DPP4 dans des échantillons de Humain.
N° du produit ABIN7472924

Aperçu rapide pour DPP4 anticorps (ABIN7472924)

Antigène

Voir toutes DPP4 Anticorps
DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reactivité

  • 133
  • 45
  • 43
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 87
  • 68
  • 17
  • 2
  • 1
Souris

Clonalité

  • 94
  • 79
  • 1
Monoclonal

Conjugué

  • 86
  • 24
  • 16
  • 13
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp DPP4 est non-conjugé

Application

  • 76
  • 75
  • 50
  • 34
  • 34
  • 31
  • 29
  • 22
  • 6
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Specificité

    Recognizes human Dipeptidyl peptidase 4, also known as Adenosine deaminase complexing protein 2, CD26, TP103, ADABP or DPP IV. CD26 is a 766 amino acid ~110 kD single pass type II transmembrane glycoprotein expressed by activated T cells, B cells and macrophages. A soluble form of CD26 can be derived by cleavage of the membrane bound form between residues 38-39. CD26 acts as a functional receptor for the pathogenic Middle East respiratory syndrome coronavirus [MERS-CoV], a severe and frequently fatal disease in humans and marmosets sharing identical CD26 sequence at the site of interaction with the MERS-CoV spike protein. Has been used successfully for the immunohistochemical detection of CD26 on formalin fixed, paraffin embedded tissues and the demonstration of elevated CD26 expression in thyroid neoplasia. Has also been used for the immunohistochemical detection of CD26 on cryostat sections using both immunoperoxidase and immunofluorescence staining in liver biopsies from NASH patients.

    Purification

    Protein G purified

    Immunogène

    Human T-cell leukaemia cells (T-CLL).

    Type of Immunogen: Cells

    Isotype

    IgG1
  • Indications d'application

    Approved: Flo (1:50 - 1:100), IHC, IHC-Fr, IP

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS,  pH 7.4, 0.09 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid freeze-thaw cycles.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Antigène

    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

    Autre désignation

    DPP4 / CD26

    Sujet

    Name/Gene ID: DPP4
    Subfamily: Serine S9B
    Family: Protease

    Synonyms: DPP4, ADCP-2, ADABP, Dipeptidyl peptidase IV, Dipeptidyl-peptidase 4, DPPIV, ADCP2, T-cell activation antigen CD26, CD26, CD26 antigen, Dipeptidyl peptidase 4, Dipeptidylpeptidase 4, DPP IV, TP103

    ID gène

    1803

    UniProt

    P27487

    Pathways

    Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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