CD55 anticorps
Aperçu rapide pour CD55 anticorps (ABIN7470770)
Antigène
Voir toutes CD55 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Recognizes the CD55 antigen, a 70kD glycoprotein also known as Decay Accelerating Factor (DAF). Distributed on erythrocytes and other circulating blood cells and also on cells in non-hemopoietic tissue particularly epithelium and endothelium. Found specifically at the fetal-maternal interfaces in placenta. CD55 has reduced expression on individuals with paroxysmal nocturnal hemoglobinuria. Has a functional binding affinity to erythrocytes of 8.7 x 107 M-1. The antigen is pronase and trypsin resistant and chymotrypsin sensitive. Recognizes the consensus region 3 of the DAF molecule, which contains the functional site, and the antibody blocks the function of DAF.
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Purification
- Protein G purified
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Immunogène
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Human fibroblast cell line.
Type of Immunogen: Cells -
Isotype
- IgG1
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Indications d'application
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Approved: Flo, IP
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL Method sheets are available on request. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- deionized water
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Concentration
- Lot specific
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Buffer
- 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- CD55 (Complement Decay-Accelerating Factor (CD55))
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Autre désignation
- CD55
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Sujet
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Name/Gene ID: CD55
Synonyms: CD55, CD55 antigen, Decay-accelerating factor, TC, CR, CROM, DAF -
ID gène
- 1604
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UniProt
- P08174
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Pathways
- Système du Complément, Regulation of Leukocyte Mediated Immunity
Antigène
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