CD40 anticorps (Extracellular Domain)

N° du produit ABIN212959

Cet anticorps Rat Monoclonal détecte spécifiquement CD40 dans FACS, ELISA, IHC et IHC (fro). Il présente une réactivité envers Souris.

Aperçu rapide pour CD40 anticorps (Extracellular Domain) (ABIN212959)

Antigène: CD40

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD40 est non-conjugé

Application: Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 3-23

Détail du produit anti-CD40 anticorps

Épitope: Extracellular Domain

Specificité: Recognizes the murine CD40 cell surface glycoprotein. It does not react with normal mouse Ig or with human IgG1 and will stain most mature mouse B cells. It does not cross react with mouse T cells. The specificity ofwas demonstrated by ELISA and flow cytometry using BHK cells transfected with mouse CD40. Is a powerful activator of normal B cells especially in the presence of IL-4.

Purification: Protein G purified

Immunogène: Extracellular Domain of Mouse CD40 and the Fc portion of Human IgG1.

Type of Immunogen: Fusion protein

Isotype: IgG2a

Information d'application

Indications d'application: Approved: ELISA, Flo (1:50 - 1:100), IHC, IHC-Fr

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur CD40

Antigène: CD40

Autre désignation: CD40

Sujet: Name/Gene ID: CD40
Family: TNF Receptor

Synonyms: CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5

ID gène: 958

UniProt: P25942

Pathways: Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints