GJB2 anticorps (Cytoplasmic Domain)
Aperçu rapide pour GJB2 anticorps (Cytoplasmic Domain) (ABIN215079)
Antigène
Voir toutes GJB2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Cytoplasmic Domain
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Specificité
- Reacts predominantly with Connexin 26. By immunoblot analysis, a 26kD protein from mouse liver membrane, mouse brain extract and rat brain extract was detected (note: samples were not boiled prior to running SDS-PAGE). A few cross-reactive bands were detected in the 45-50kD range. The identity of these proteins has yet to be confirmed, however, it is possible these bands represent dimeric forms of the Connexin 26 protein. Immunohistochemical staining of frozen sections of human cochlea showed positive reactivity for Connexin 26.
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Purification
- Immunoaffinity purified
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Immunogène
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Peptide corresponding to a portion of the cytoplasmic loop of rat connexin 26.
Type of Immunogen: Synthetic peptide -
Isotype
- IgG
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Indications d'application
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Approved: ELISA, IF, IHC, IHC-Fr, WB
Usage: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunohistochemistry. ELISA: 0.1-1.0 mg/mL. Western Blot: 0.5 mg/mL. Immunohistochemistry (frozen): 10 mg/mL. Immunofluorescence. -
Commentaires
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Target Species of Antibody: Rat
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.2, 0.1 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))
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Autre désignation
- GJB2 / CX26 / Connexin 26
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Sujet
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Name/Gene ID: GJB2
Subfamily: Connexin
Family: Ion Channel
Synonyms: GJB2, Connexin 26, Connexin-26, DFNB1A, DFNA3, DFNB1, Gap junction protein beta 2, KID, HID, PPK, NSRD1, CX26, DFNA3A -
ID gène
- 2706
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UniProt
- P29033
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Pathways
- Sensory Perception of Sound, Cell-Cell Junction Organization
Antigène
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