Estrogen Receptor alpha anticorps (AA 1-21)

N° du produit ABIN215829

Cet anticorps anti-Estrogen Receptor alpha Polyclonal Lapin (ABIN215829) détecte spécifiquement Estrogen Receptor alpha dans WB, IHC, IHC (p), ICC et IHC (fro). L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Lapin, Singe, Cheval et Hamster.

Aperçu rapide pour Estrogen Receptor alpha anticorps (AA 1-21) (ABIN215829)

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reactivité: Humain, Souris, Rat, Lapin, Singe, Cheval, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Estrogen Receptor alpha est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Estrogen Receptor alpha anticorps

Épitope: AA 1-21

Specificité: Recognizes human and rat endogenous ER alpha. Detects a band of ~64kD by Western blot. Does not cross-react with ER beta. This sequence is completely conserved in rat and mouse ER alpha and is highly conserved in sheep, porcine, canine, bovine and chicken ER alpha.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Tamarin, Mouse, Rat, Hamster, Cat, Rabbit, Horse (100%) Panda, Bovine, Pig (95%) Sheep, Opossum (90%) Turkey, Chicken (86%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide corresponding to aa 1-21 (M1TMTLHTKASGMALLHQIQGN21) of N-terminal human ER (estrogen receptor ). This sequence is completely conserved in rat and mouse ER and is highly conserved in sheep, pig, dog, bovine and chicken ER. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Tamarin, Mouse, Rat, Hamster, Cat, Rabbit, Horse (100%), Panda, Bovine, Pig (95%), Sheep, Opossum (90%), Turkey, Chicken (86%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: ICC, IHC, IHC-Fr, IHC-P, WB (1 μg/mL)

Usage: Suitable for use in Immunocytochemistry, Immunohistochemistry and Western Blot. Immunohistochemistry (frozen, paraffin sections):1-5 μg/mL. Western Blot:1 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Epitope-affinity purified IgG in PBS, 1 mg/mL BSA, 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C
Long term: -20°C.

Détails sur Estrogen Receptor alpha

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Autre désignation: ER Alpha / Estrogen Receptor

Sujet: Name/Gene ID: ESR1
Subfamily: NR3 Steroid receptor
Family: NHR

Synonyms: ESR1, Era, ERalpha, Estrogen receptor, Estradiol receptor, ER-alpha, Estrogen receptor 1, NR3A1, ER, ESR, ESRA, Estrogen receptor alpha

ID gène: 2099

UniProt: P03372

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly