BRIP1 anticorps (pSer990) (HRP)

N° du produit ABIN2170685

L’anticorps anti-BRIP1 Polyclonal Lapin est utilisé pour la détection de BRIP1 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IHC (p) et IHC (fro).

Aperçu rapide pour BRIP1 anticorps (pSer990) (HRP) (ABIN2170685)

Antigène: BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRIP1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-BRIP1 anticorps (HRP)

Épitope: pSer990

Specificité: This phosphorylation site is homologous to that of Ser921 in Bovine.

Réactivité croisée: Humain, Souris

Homologie: Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human BRIP1 around the phosphorylation site of Ser990

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BRIP1

Antigène: BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))

Autre désignation: BRIP1

Sujet:

Synonyms: OF, BACH1, FANCJ, Fanconi anemia group J protein, Protein FACJ, ATP-dependent RNA helicase BRIP1, BRCA1-associated C-terminal helicase 1, BRCA1-interacting protein C-terminal helicase 1, BRCA1-interacting protein 1, BRIP1

Background: DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.

ID gène: 83990

UniProt: Q9BX63

Pathways: Réparation de l'ADN