Transferrin Receptor anticorps

N° du produit ABIN217766

L’anticorps Rat Monoclonal anti-Transferrin Receptor a été validé pour FACS, IHC, IP, IHC (fro) et Func. Il convient pour détecter Transferrin Receptor dans des échantillons de Souris.

Aperçu rapide pour Transferrin Receptor anticorps (ABIN217766)

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin Receptor est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: 8D3

Détail du produit anti-Transferrin Receptor anticorps

Specificité: Recognizes mouse CD71, a 95kD cell surface protein that is otherwise known as transferrin receptor. CD71 is a major iron-binding protein, which plays a key role in the transport of iron into cells that require it. In mice, CD71 is widely expressed on a variety of cells, including Sertoli cells and cells which form the blood brain barrier (BBB) in the central nervous system. Recognizes native, soluble and denatured forms of murine CD71. Binding of the 8D3 antibody to CD71 does not inhibit the proliferation of cell lines tested, and does not interfere with the uptake of iron into cells. The antibody has been used as a BBB transporter vector in mice and is suitable for studying CD71 expression, and iron uptake into different tissues, in the mouse.

Purification: Protein G purified

niveau d'endotoxine: Low Endotoxin

Immunogène: Mouse transformed endothelioma cell line t. end1.

Isotype: IgG2a

Information d'application

Indications d'application: Approved: Flo (1:100 - 1:200), Func, IHC, IHC-Fr, IP

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 Method sheets are available on request.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4.

Conseil sur la manipulation: Aliquot to Avoid freeze/thaw cycles. Store undiluted.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot to avoid freeze-thaw cycles. Store undiluted.

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: CD71 / Transferrin Receptor

Sujet: Name/Gene ID: TFRC
Subfamily: Metallopeptidase M28B
Family: Protease

Synonyms: TFRC, CD71, TFR1, TRFR, TFR, TR, CD71 antigen, p90, T9, Transferrin receptor, Transferrin receptor protein 1

ID gène: 7037

Pathways: Transition Metal Ion Homeostasis