BAFF anticorps

N° du produit ABIN217771

Cet anticorps Souris Monoclonal détecte spécifiquement BAFF dans ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour BAFF anticorps (ABIN217771)

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BAFF est non-conjugé

Application: ELISA

Détail du produit anti-BAFF anticorps

Specificité: Recognizes CD257 (otherwise known as BAFF/BLyS), a 285 amino acid type II transmembrane protein and member of the tumor necrosis factor (TNF) superfamily of ligands, which acts as a B and T cell stimulator and plays a role in the development of autoimmune diseases such as systemic lupus erythematosus. CD257 is expressed by monocytes, macrophages, T cells and dendritic cells and acts through binding to CD267 (TACI), CD269 (BCMA) and CD268 (BAFFR) receptors, the latter interaction playing a critical role in the activation, survival, differentiation and proliferation of B cells.

Purification: Protein A purified

Immunogène: Recombinant human CD257.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA (5 - 6 μg/mL)

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.2.

Détails sur BAFF

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Autre désignation: BAFF

Sujet: Name/Gene ID: TNFSF13B
Family: TNF

Synonyms: TNFSF13B, B-cell-activating factor, BAFF, ApoL related ligand TALL-1, B-lymphocyte stimulator, CD257, BLYS, Delta4 BAFF, Delta BAFF, TALL-1, TALL1, ZTNF4, THANK, B lymphocyte stimulator, CD257 antigen, TNFSF20

ID gène: 10673

UniProt: Q9Y275

Pathways: Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response