Phospholamban anticorps (pSer16) (PE)
Aperçu rapide pour Phospholamban anticorps (pSer16) (PE) (ABIN2178506)
Antigène
Voir toutes Phospholamban (PLN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer16
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic phosphopeptide derived from human Cardiac phospholamban around the phosphorylation site of Ser16
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Isotype
- IgG
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Indications d'application
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FCM: (1:20-100)
Optimal working dilution should be determined by the investigator. -
Commentaires
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Exitation/Emission: 480,565nm/578nm
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at 4 °C for 12 months.
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- Phospholamban (PLN)
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Autre désignation
- Plb
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Sujet
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Defects in PLN are the cause of cardiomyopathy dilated type 1P (CMD1P) . Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.Defects in PLN are the cause of cardiomyopathy familial hypertrophic type 18 (CMH18) . CMH18 is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
Synonyms: Phospholamban phospho S16, p-Phospholamban phospho S16, p-PLBS16, Cardiac phospholamban, CMD1P, PLB, PLN, PPLA_HUMAN. -
ID gène
- 5350
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Pathways
- Negative Regulation of Transporter Activity
Antigène
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