Phospholamban anticorps (pThr17)

N° du produit ABIN650834

L’anticorps anti-Phospholamban Polyclonal Lapin est utilisé pour la détection de Phospholamban dans des échantillons de Humain et Rat. Il a été validé pour WB et DB.

Aperçu rapide pour Phospholamban anticorps (pThr17) (ABIN650834)

Antigène: Phospholamban (PLN)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Phospholamban est non-conjugé

Application: Western Blotting (WB), Dot Blot (DB)

Clone: RB24137

Détail du produit anti-Phospholamban anticorps

Épitope: pThr17

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PLB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T17 of human PLB.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000. DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur Phospholamban

Antigène: Phospholamban (PLN)

Autre désignation: PLB

Sujet: Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases, whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.

Poids moléculaire: 6109

ID gène: 5350

NCBI Accession: NP_002658

UniProt: P26678

Pathways: Negative Regulation of Transporter Activity