APEX1 anticorps

N° du produit ABIN219055

Cet anticorps Lapin Polyclonal détecte spécifiquement APEX1 dans WB, IHC, ICC, IHC (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour APEX1 anticorps (ABIN219055)

Antigène: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APEX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-APEX1 anticorps

Specificité: Recognizes human APE. Detects a band of ~37kD by Western Blot. Species cross-reactivity: mouse and rat.

Purification: Immunoaffinity purified

Immunogène: Recombinant human APE.

Type of Immunogen: Recombinant protein

Isotype: IgG

Information d'application

Indications d'application: Approved: ICC (1:100 - 1:200), IHC, IHC-Fr, IHC-P, WB (1:300 - 1:1000)

Usage: Suitable for use in Immunocytochemistry, Western Blot and Immunohistochemistry. Also suitable for use in Apoptosis assay (following TUNEL assay using Boehringer-Mannheim TUNEL assay kit). Western Blot: 1:300-1:1000 on HL60 and HeLa cells using ECL. Antibody may be used 1-4X in the binding solution depending on the cells/cell lines. Immunohistochemistry: 1:100-1:200 on frozen and paraffin sections from human and rat tissues. Immunocytochemistry: 1:100-1:200 on cytospin preparations of cells fixed in paraformaldehyde. Apoptosis (TUNEL) assay: perform antibody staining AFTER the. TUNEL assay.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS. Contains no preservatives.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Détails sur APEX1

Antigène: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Autre désignation: APEX1 / APE1

Sujet: Name/Gene ID: APEX1

Synonyms: APEX1, AP endonuclease class I, AP lyase, APE, APE-1, APEN, APE1, APEX nuclease, Redox factor-1, AP endonuclease 1, APEX, APX, Protein REF-1, REF-1, REF1

ID gène: 328

UniProt: P27695

Pathways: Réparation de l'ADN, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus