FABP1 anticorps

N° du produit ABIN2191917

Cet anticorps anti-FABP1 est un anticorps Souris Monoclonal détectant FABP1 dans WB, IHC (p), FACS et IA. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour FABP1 anticorps (ABIN2191917)

Antigène: FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FABP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunoassay (IA)

Clone: L2B10

Détail du produit anti-FABP1 anticorps

Réactivité croisée (Details): Cross reactivity: : Baboon L-FABP : Yes, Dog L-FABP : Yes, Rat L-FABP : Yes, Swine L-FABP : Yes, Human H-FABP Weak

Stérilité: 0.2 μm filtered

Isotype: IgG2b

Information d'application

Indications d'application: For immunohistology and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

Restrictions: For Research Use only

Stockage

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Date de péremption: 12 months

Références pour anticorps anti-FABP1 (ABIN2191917)

Bax, Siersema, Haringsma, Kuipers, Vos, Van Dekken, Van Vliet, Kusters: "High-grade dysplasia in Barrett's esophagus is associated with increased expression of calgranulin A and B." dans: Scandinavian journal of gastroenterology, Vol. 42, Issue 8, pp. 902-10, (2007) (PubMed).

Détails sur FABP1

Antigène: FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

Autre désignation: Liver Fatty Acid Binding Protein

Sujet: The monoclonal antibody L2B10 recognizes human liver fatty acid binding protein (L-FABP) of both natural and recombinant origin. The L-FABP protein is derived from the human FABP1 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. L-FABP is localized in the liver, kidney and intestinal epithelium. The monoclonal antibody L2B10 is useful to detect ischemic areas of human liver. Furthermore, the antibody can be used for the purification of human L-FABP. Aliases FABP1

Pathways: Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha