FABP1 anticorps

N° du produit ABIN2191918

Cet anticorps Souris Monoclonal détecte spécifiquement FABP1 dans IA. Il présente une réactivité envers Humain.

Aperçu rapide pour FABP1 anticorps (ABIN2191918)

Antigène: FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FABP1 est non-conjugé

Application: Immunoassay (IA)

Clone: K5A6

Détail du produit anti-FABP1 anticorps

Réactivité croisée (Details): Cross reactivity: Rat L-FABP : Yes, (weak) Baboon L-FABP : Yes, Human H-FABP : Yes, (weak)

Stérilité: 0.2 μm filtered

Isotype: IgG1

Information d'application

Indications d'application: For immunohistochemistry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

Restrictions: For Research Use only

Stockage

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.

Détails sur FABP1

Antigène: FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

Autre désignation: Liver Fatty Acid Binding Protein

Sujet: The monoclonal antibody K5A6 recognizes human liver fatty acid binding protein (L-FABP) of both natural and recombinant origin. The L-FABP protein is derived from the human FABP1 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. L-FABP is localized in the liver, kidney and intestinal epithelium. The monoclonal antibody K5A6 is useful to detect ischemic areas of human liver. Aliases Fatty acid-binding protein 1

Pathways: Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha