C5 anticorps

N° du produit ABIN2191951

Cet anticorps Souris Monoclonal détecte spécifiquement C5 dans WB et IA. Il présente une réactivité avec des échantillons de Humain.Il a été cité dans 1 publication.

Aperçu rapide pour C5 anticorps (ABIN2191951)

Antigène: C5 (Complement Component 5 (C5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp C5 est non-conjugé

Application: Western Blotting (WB), Immunoassay (IA)

Clone: 568

Détail du produit anti-C5 anticorps

Stérilité: 0.2 μm filtered

Information d'application

Indications d'application: It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.

Restrictions: For Research Use only

Stockage

Buffer: PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Date de péremption: 12 months

Références pour anticorps anti-C5 (ABIN2191951)

Mollnes, Klos, Tschopp: "Identification of a human C5 beta-chain epitope exposed in the native complement component but concealed in the SC5b-9 complex." dans: Scandinavian journal of immunology, Vol. 28, Issue 3, pp. 307-12, (1988) (PubMed).

Détails sur C5

Antigène: C5 (Complement Component 5 (C5))

Autre désignation: c5/c5b

Sujet: Monoclonal antibody 568 reacts with an epitope on C5 and on C5b. C5 is involved in the activation of the lythic pathway within the complement system which is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead via C3 to the cleavage of the fifth complement component C5 into C5a and C5b. C5b initiates the assembly of the membrane attack complex (MAC) that mediates cytolysis.

Pathways: Système du Complément, Carbohydrate Homeostasis