APC anticorps (AA 1-433)

N° du produit ABIN224804

L’anticorps anti-APC Monoclonal produit chez le Souris a été validé pour WB, IHC et IHC (fro). Il convient pour la détection de APC dans des échantillons provenant de Humain. }

Aperçu rapide pour APC anticorps (AA 1-433) (ABIN224804)

Antigène: APC (Adenomatous Polyposis Coli (APC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp APC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-APC anticorps

Épitope: AA 1-433

Specificité: Recognizes the N-terminal region of the human APC protein. Epitope Mapping: Performed by differential in vitro expression of the N-terminal region of the APC gene by using the protein truncation test. Found to bind to APC in the region between aa135-422 (exon 2-3). Species cross-reactivity: Does not cross-react with mouse.

Purification: Protein A purified

Immunogène: Synthetic peptide corresponding to aa1-433 N-terminal fragment of human APC (Adenomatous Polyposis Coli gene Chr 5q) (coupled to maltose binding protein). Cellular localization: cytoplasmic and nuclear.

Type of Immunogen: Synthetic peptide

Isotype: IgG1

Information d'application

Indications d'application: Approved: IHC, IHC-Fr, WB

Usage: Suitable for use in Immunohistochemistry and Western Blot. Immunohistochemistry: Acetone fixed, frozen sections. Positive control: Colon cell line HCT116, SW480 and SW837 extracts.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 40 % glycerol.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur APC

Antigène: APC (Adenomatous Polyposis Coli (APC))

Autre désignation: APC

Sujet: Name/Gene ID: APC

Synonyms: APC, Adenomatosis polyposis coli, Adenomatous polyposis coli, BTPS2, Deleted in polyposis 2.5, DP2, DP2.5, FPC, GS, Protein APC, PPP1R46, DP3

ID gène: 324

UniProt: P25054

Pathways: Signalisation WNT, Stem Cell Maintenance, Cell-Cell Junction Organization