PKM2 anticorps (Asn491, C-Term) (HRP)

N° du produit ABIN2336512

Cet anticorps Lapin Polyclonal détecte spécifiquement PKM2 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour PKM2 anticorps (Asn491, C-Term) (HRP) (ABIN2336512)

Antigène: PKM2 (Pyruvate Kinase M2 (PKM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKM2 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA

Détail du produit anti-PKM2 anticorps (HRP)

Épitope: Asn491, C-Term

Specificité: Recognizes human PKM2.

Réactivité croisée: Humain, Souris

Réactivité croisée (Details): Calculated cross reactivity: Hu Mo

Attributs du produit: PKM2, CT (N491) (Pyruvate Kinase, Isozymes M1/M2, Pyruvate Kinase Muscle Isozyme, Cytosolic Thyroid Hormone-binding Protein, CTHBP, Opa-interacting Protein 3, OIP-3, Pyruvate Kinase 2/3, Thyroid Hormone-binding Protein 1, THBP1, Tumor M2-PK, p58, PKM, OIP3, PK2, PK3) (Azide free) (HRP)

Purification: Purified by Protein G affinity chromatography.

Immunogène: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 476-505 in the C-terminal region of human PKM2, UniProt Accession #NP_002645.

Isotype: IgG

Information d'application

Indications d'application: Optimal working conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.

Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Détails sur PKM2

Antigène: PKM2 (Pyruvate Kinase M2 (PKM2))

Autre désignation: PKM2

Sujet: PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

NCBI Accession: NP_002645

UniProt: P14618

Pathways: L'effet Warburg