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FKBP8 anticorps (Internal Region)

FKBP8 Reactivité: Humain, Souris, Rat ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN233735
$482.90
Plus frais de port $45.00 et $20.00 pour carboglace
Destination: Etats-Unis
Envoi sous 1 à 2 jours ouvrables
  • Antigène Voir toutes FKBP8 Anticorps
    FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))
    Épitope
    • 15
    • 14
    • 9
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 61
    • 38
    • 27
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 66
    • 7
    • 5
    Lapin
    Clonalité
    • 73
    • 4
    Polyclonal
    Conjugué
    • 32
    • 9
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FKBP8 est non-conjugé
    Application
    • 46
    • 30
    • 14
    • 14
    • 10
    • 6
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Specificité
    This product was protein A purified from monospecific antiserum by immunoaffinity chromatography using protein A coupled to agarose beads.  This antibody is specific for human FKBP8 protein.  A BLAST analysis was used to suggest partial cross-reactivity with FKBP8 from mouse and rat sources based on ~93% homology with the immunizing sequence.  Cross-reactivity with FKBP8 from other sources has not been determined.
     Réactivité croisée
    Souris, Rat (Rattus)
    Attributs du produit
    FKBP8 (also known as FK506-binding protein 38) is a member of the immunophilin family that has been implicated to play an important role in apoptosis through its involvement in the mechanism that targets Bcl-2 and Bcl-xL to the outer mitochondrial membrane (OMM). Suppression of endogenous FKBP8 by RNAi or transfection of a mutant FKBP8 missing the transmembrane domain necessary for mitochondrial insertion, resulted in the translocation of Bcl-2 and Bcl-xL from the OMM to the cytosol. It has also been suggested that FKBP8 may play
    Purification
    affinity purified
    Stérilité
    Sterile filtered
    Immunogène
    This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human FKBP8 protein.
    Immunogen Type: Peptide
    Isotype
    IgG
  • Indications d'application
    This protein A purified antibody has been tested for use in ELISA and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 64 kDa in size corresponding to FKBP8 by western blotting in the appropriate cell lysate or extract.
    Commentaires

    Gene Name: FKBP8

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.
    Date de péremption
    3 months
  • Antigène
    FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))
    Autre désignation
    FKBP8 (FKBP8 Produits)
    Synonymes
    FKBP8, fkbp8, 38kDa, FKBP-38, FKBP-8, Fkbp38, zgc:77672, FKBP38, FKBPr38, FK506 binding protein 8, FK506 binding protein 8 L homeolog, FKBP8, fkbp8, Fkbp8, fkbp8.L
    Sujet
    FKBP8 (also known as FK506-binding protein 38) is a member of the immunophilin family that has been implicated to play an important role in apoptosis through its involvement in the mechanism that targets Bcl-2 and Bcl-xL to the outer mitochondrial membrane (OMM). Suppression of endogenous FKBP8 by RNAi or transfection of a mutant FKBP8 missing the transmembrane domain necessary for mitochondrial insertion, resulted in the translocation of Bcl-2 and Bcl-xL from the OMM to the cytosol. It has also been suggested that FKBP8 may play
    Synonyms: 38 kDa FK 506 binding protein homolog antibody, 38kDa antibody, FK506 binding protein 8 antibody, FKBP 38 antibody
    ID gène
    23770, 52630440
    UniProt
    Q14318
    Pathways
    Autophagy
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