IL17RA anticorps (C-Term)

N° du produit ABIN233846

N° du produit (Fournisseur): 600-401-a48

L’anticorps Lapin Polyclonal anti-IL17RA a été validé pour WB, ELISA, IHC et DB. Il convient pour détecter IL17RA dans des échantillons de Souris.

Aperçu rapide pour IL17RA anticorps (C-Term) (ABIN233846)

Antigène: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL17RA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Dot Blot (DB)

Détail du produit anti-IL17RA anticorps

Épitope: C-Term

N° du produit (Fournisseur): 600-401-a48

Fournisseur: Rockland

Fonction: IL-7 Receptor Alpha Chain Antibody

Réactivité croisée (Details): This antibody is specific for mouse IL-7 receptor protein.

Attributs du produit: Synonyms: rabbit anti-IL-7 Receptor alpha chain antibody, rabbit anti-Interleukin-7 Receptor alpha chain antibody, IL7R alpha antibody, IL-7R alpha, IL 7R α, Interleukin7 Receptor, Interleukin 7 receptor alpha chain antibody, Interleukin 7 receptor α antibody

Purification: This product was affinity purified from monospecific antiserum by immunoaffinity chromatography using peptide coupled to agarose beads.

Stérilité: Sterile filtered

Immunogène:

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminus of mouse IL-7 receptor protein.

Immunogen Type: Conjugated Peptide

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry Dilution: User Optimized

Application Note: This affinity purified antibody has been tested for use in ELISA and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 55 kDa in size corresponding to IL-7 receptor protein by western blotting in the appropriate cell lysate or extract.

Western Blot Dilution: 1:1,000 - 1:10,000

ELISA Dilution: 1:5,000-1:50,000

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.82 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store IL-7 Receptor Alpha Chain Antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur IL17RA

Antigène: IL17RA (Interleukin 17 Receptor A (IL17RA))

Autre désignation: IL17R

Sujet: Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Interleukin-7 is a glycoprotein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R), the active receptor is an alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules.  The human and mouse sequence is nearly identical.  In humans, severe combined immunodeficiency is caused by genetic defects in IL-7 receptor. The tyrosine residue at the 449 position is a critical signaling site of the intracellular domain of IL-7 receptor. This site is rapidly phosphorylated by janus kinases after the IL-7 receptor is engaged. IL-7 Receptor Alpha Chain Antibody is ideal for investigators interested in Immunology research.

ID gène: 16197, 45269152

UniProt: P16872

Pathways: SARS-CoV-2 Protein Interactome