Cet anticorps anti-Ancient Ubiquitous Protein 1 Polyclonal Lapin (ABIN2422581) détecte spécifiquement Ancient Ubiquitous Protein 1 dans WB, IHC et ELISA.
L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.
Aup1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB 1:500-1:2000, IHC 1:50-1:200
Restrictions
For Research Use only
Format
Liquid
Concentration
0.4 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Agent conservateur
Sodium azide
Conseil sur la manipulation
Avoid freeze / thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
Ancient Ubiquitous Protein 1 (Aup1)
Autre désignation
AUP1
Sujet
This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.