TLR3 anticorps

N° du produit ABIN2422741

Cet anticorps Lapin Polyclonal détecte spécifiquement TLR3 dans IHC et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TLR3 anticorps (ABIN2422741)

Antigène: TLR3 (Toll-Like Receptor 3 (TLR3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR3 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-TLR3 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human TLR3

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TLR3

Antigène: TLR3 (Toll-Like Receptor 3 (TLR3))

Autre désignation: TLR3

Sujet: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons.

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades