GRK4 anticorps

N° du produit ABIN2428193

L’anticorps anti-GRK4 Polyclonal produit chez le Lapin a été validé pour WB, ELISA et IHC. Il convient pour la détection de GRK4 dans des échantillons provenant de Humain, Souris et Rat. }

Aperçu rapide pour GRK4 anticorps (ABIN2428193)

Antigène: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRK4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-GRK4 anticorps

Purification: Antigen affinity purification

Immunogène: Recombinant protein of human GRK4

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C/-80 °C

Stockage commentaire: Store at -20°C (regular) and -80°C (long term).

Détails sur GRK4

Antigène: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Autre désignation: GRK4

Sujet: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin, the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin. GRK4-alpha and GRK4-gamma phosphorylate DRD3. Phosphorylates ADRB2.
Synonyms: IT11, GPRK4, GRK4a, GPRK2L

Poids moléculaire: Calculated MW: 67 kDa

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling