RAB27A anticorps

N° du produit ABIN2443836

Cet anticorps anti-RAB27A Polyclonal Lapin (ABIN2443836) détecte spécifiquement RAB27A dans WB et IP. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour RAB27A anticorps (ABIN2443836)

Antigène: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB27A est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-RAB27A anticorps

Fonction: Rab27a Rabbit Polyclonal Antibody

Specificité: The antibody recognizes the human Rab27a protein.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: If reconstituted with deionized water in 100 μL: WB: 1:1000 (Recommended blocking solution: Donkey Serum 20 % ). IP: native conditions with 0.2 % TritonX-100. Optimal dilution has to be determined by the user.

Buffer: Lyophilized serum

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Date de péremption: 24 months

Détails sur RAB27A

Antigène: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Autre désignation: Rab27a

Sujet:

Ras-related protein Rab-27A, RAB27A, GS2, HsT18676, RAB27, RAM, member RAS oncogene family

Ras-related protein Rab-27a (Rab27a) belongs to the small GTPase superfamily. The protein is membrane-bound and is involved in protein transport and small GTPase-mediated signal transduction. Rab27a plays a role in cytotoxic granule exocytosis in lymphocytes. Rab27a is widely expressed with considerable expression in pancreatic islets and pituitary tissue, and low expression in the brain. Defects in RAB27A are a cause of Griscelli syndrome type 2 (GS2), a rare autosomal recessive disorder.

UniProt: P51159

Pathways: Peptide Hormone Metabolism