CBX3 anticorps (C-Term)

N° du produit ABIN2452035

Cet anticorps anti-CBX3 est un anticorps Lapin Polyclonal détectant CBX3 dans WB, IF et ChIP-seq. Adapté pour Humain et Hamster. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour CBX3 anticorps (C-Term) (ABIN2452035)

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Reactivité: Humain, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ChIP DNA-Sequencing (ChIP-seq)

Détail du produit anti-CBX3 anticorps

Épitope: C-Term

Réactivité croisée (Details): Expected to react with chicken, Xenopus, Drosophila, and zebra fish orthologs due to the sequence identity of the immunogen.

Attributs du produit: The product is prepared by immunizing rabbit with the synthetic peptide WHSCPEDEAQ-C corresponding to the C-terminal sequence of human HP1γ and purified by affinity purification with the peptide. The antiserum preparation has been directed by Prof. T. Haraguchi.

Purification: Affinity purified

Stérilité: Sterile filtered

Isotype: IgG

Information d'application

Indications d'application: 1) Western blotting: 1/2,000~1/10,000
2) Immunofluorescence staining
3) Chromatin immunoprecipitation (ChIP)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.75 mg/mL

Buffer: 0.12 M sodium phosphate buffer ( pH 7.4), 50 % glycerol

Agent conservateur: Azide free

Stock: -20 °C/-80 °C

Stockage commentaire: -20 C (For long term storage: -70 C)

Références pour anticorps anti-CBX3 (ABIN2452035)

Lomberk, Wallrath, Urrutia: "The Heterochromatin Protein 1 family." dans: Genome biology, Vol. 7, Issue 7, pp. 228, (2007) (PubMed).

Wang, Koyama, Nishida, Haraguchi, Reith, Tsukamoto: "The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells." dans: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4028-40, (2006) (PubMed).

Kametaka, Takagi, Hayakawa, Haraguchi, Hiraoka, Yoneda: "Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 7, Issue 12, pp. 1231-42, (2002) (PubMed).

Détails sur CBX3

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Autre désignation: HP1gamma/CBX3

Sujet: Heterochromatin protein 1 (HP1) is a major component of heterochromatin which plays a role in assembly of various proteins on chromatin and gene silencing. The HP1 family is evolutionally conserved, with members in fungi, plants and animals but not prokaryotes, and there are multiple members within the same species. The HP1 family proteins are encoded by a class of genes known as the chromobox (CBX) genes. In humans, HP1γ is encoded by the Chromobox homolog 3 (CBX3) gene. HP1γ has been observed to interact directly or indirectly with several non-histone proteins with a wide variety of functions.

UniProt: Q13185