KPNA4 anticorps (full length)

N° du produit ABIN2452037

Il existe 3+ publications pour ce produit. L’anticorps anti-KPNA4 Monoclonal Rat est utilisé pour la détection de KPNA4 dans des échantillons de Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour KPNA4 anticorps (full length) (ABIN2452037)

Antigène: KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp KPNA4 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 3D10

Détail du produit anti-KPNA4 anticorps

Épitope: full length

Specificité: Reactive with human, simian, mouse, rat, hamster, canine and bovine importin a3. This antibody doesn't recognize other importin a family including a4.

Attributs du produit: The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by proprietary chromatography processes.

Purification: Purified

Stérilité: Sterile filtered

Immunogène: Recombinant mouse importin a3 /KPNA4/ Qip 1 (full length)

Isotype: IgG2a kappa

Information d'application

Indications d'application: 1. Western blotting: 250~500 fold dilution
2. ELISA
This antibody doesn't work for immunostaining and immunoprecipitation.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol

Agent conservateur: Azide free

Stock: -20 °C/-80 °C

Stockage commentaire: -20 C (For long term storage: -70 C)

Références pour anticorps anti-KPNA4 (ABIN2452037)

Yasuhara, Shibazaki, Tanaka, Nagai, Kamikawa, Oe, Asally, Kamachi, Kondoh, Yoneda: "Triggering neural differentiation of ES cells by subtype switching of importin-alpha." dans: Nature cell biology, Vol. 9, Issue 1, pp. 72-9, (2007) (PubMed).

Yoneda: "Nucleocytoplasmic protein traffic and its significance to cell function." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 5, Issue 10, pp. 777-87, (2000) (PubMed).

Miyamoto, Imamoto, Sekimoto, Tachibana, Seki, Tada, Enomoto, Yoneda: "Differential modes of nuclear localization signal (NLS) recognition by three distinct classes of NLS receptors." dans: The Journal of biological chemistry, Vol. 272, Issue 42, pp. 26375-81, (1997) (PubMed).

Détails sur KPNA4

Antigène: KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

Autre désignation: Importin alpha 3 / Qip1KPNA4

Sujet: Importin a proteins play a pivotal role in the import of proteins from the cytoplasm to the nucleus. Importin a proteins shuttle between nucleus and cytoplasm, bind nuclear localization signal (NLS)-bearing proteins, and mediate the protein import into the nucleus with importin b. Several importin a isotypes have been identified, each exhibiting differential recognition and nuclear transport, probably via preferential binding to a particular NLS. The importin a3 (KPNA4, Qip1) is a member of the importin a family of proteins belonging to the Qip1 subfamily.

Pathways: Protein targeting to Nucleus