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NUP98 anticorps (FGxxN Motif, N-Term)

NUP98 Reactivité: Humain, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena WB, IF Hôte: Souris Monoclonal 13C2 unconjugated
N° du produit ABIN2452065
  • Antigène Voir toutes NUP98 Anticorps
    NUP98 (Nucleoporin 98kDa (NUP98))
    Épitope
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    FGxxN Motif, N-Term
    Reactivité
    • 47
    • 16
    • 12
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena
    Hôte
    • 36
    • 10
    • 2
    Souris
    Clonalité
    • 34
    • 14
    Monoclonal
    Conjugué
    • 38
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NUP98 est non-conjugé
    Application
    • 35
    • 16
    • 12
    • 11
    • 7
    • 4
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    Réactivité croisée (Details)
    Not tested in other species
    Purification
    Purified
    Stérilité
    Sterile filtered
    Immunogène
    Synthetic peptides containing conserved N-terminal sequence, GLFG, of Nup98 protein of Tetrahymena thermophila.
    Clone
    13C2
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product NUP98 Anticorps primaire
  • Indications d'application
    1) Most suitable for Western blotting,(Human,S. cerevisiae,S. pombe,Tetrahymena.)
    2) Immunofluorescence staining / Immunocytochemistry for S. cerevisiae,S. pombe and T. etrahymena.
    Not suitable for IF in human
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol. Azide- and carrier protein-free.
    Agent conservateur
    Azide free
    Stock
    -20 °C
    Stockage commentaire
    Upon arrival centrifuge briefly and store at -20 C.
  • Iwamoto, Asakawa, Ohtsuki, Osakada, Koujin, Hiraoka, Haraguchi: "Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans." dans: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 2, pp. 81-90, (2013) (PubMed).

    Iwamoto, Asakawa, Hiraoka, Haraguchi: "Nucleoporin Nup98: a gatekeeper in the eukaryotic kingdoms." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 15, Issue 7, pp. 661-9, (2010) (PubMed).

  • Antigène
    NUP98 (Nucleoporin 98kDa (NUP98))
    Autre désignation
    Nup98 (NUP98 Produits)
    Synonymes
    anticorps CG10198, anticorps CG10201, anticorps Dmel\\CG10198, anticorps Nup 96, anticorps Nup 98, anticorps Nup-98, anticorps Nup96, anticorps Nup98, anticorps Nup98-Nup96, anticorps Nup98/96, anticorps l(3)95BCd, anticorps nup145, anticorps nup98-96, anticorps GB12688, anticorps NUP98, anticorps 4732457F17, anticorps AI849286, anticorps im:7151238, anticorps zgc:113968, anticorps zgc:63593, anticorps ADIR2, anticorps NUP196, anticorps NUP96, anticorps Nucleoporin 98-96kD, anticorps nuclear pore complex protein Nup98-Nup96, anticorps nucleoporin 98, anticorps nucleoporin 98kDa, anticorps nucleoporin 98 L homeolog, anticorps Nup98-96, anticorps LOC408335, anticorps NUP98, anticorps LOC587580, anticorps Nup98, anticorps nup98, anticorps nup98.L
    Sujet
    Nucleoporin 98 (Nup98) is a component of nuclear pore complex (NPC), which is a large protein assembly embedded in the nuclear envelope and highly conserved in eukaryotes. It is localized on both nuclear and cytoplasmic side of NPC. This protein contains glycine-leucine-phenylalanine-glycine (GLFG) amino acid repeats and plays a critical role in nuclear trafficking. Nup98 also plays a specific role in the RNA export. In addition, Nup98 plays roles in several important biological events such as gene expression, mitotic checkpoint, and pathogenesis Nup98 gene is fused to a variety of partner genes in human myeloid and T-cell malignancies via chromosomal translocation. In ciliates, a unicellular organism having two functionally distinct nuclei, GLFG-Nup98 is present in one of the nuclei and a distinct Nup98 ortholog is present in the other nucleus, and these different Nup98s participate in a nucleus-selective transport mechanism.
    UniProt
    P52948
    Pathways
    Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome
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