PSMD6 anticorps
Aperçu rapide pour PSMD6 anticorps (ABIN2452115)
Antigène
Voir toutes PSMD6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Product: Rabbit polyclonal antibody affinity purified with recombinant Rpn7p
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Purification
- Affinity purified
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Immunogène
- Recombinant yeast Rpn7p expressed in E. coli
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Isotype
- IgG
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Indications d'application
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1) Western blotting: ~1000 fold dilution
2) Immunoprecipitation Not tested for other applications. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 100 mM NaCl, 10 mM Tris-HCl pH 7.4, 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- To avoid repeated freezing and thawing, store the antibody solution in aliquots.
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Stock
- -20 °C
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Stockage commentaire
- -20 C. To avoid repeated freezing and thawing, store the antibody solution in aliquots.
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: "The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome." dans: Molecular biology of the cell, Vol. 18, Issue 2, pp. 569-80, (2007) (PubMed).
: "Rpn7 Is required for the structural integrity of the 26 S proteasome of Saccharomyces cerevisiae." dans: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27168-76, (2004) (PubMed).
: "Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. ..." dans: Trends in biochemical sciences, Vol. 23, Issue 7, pp. 244-5, (1998) (PubMed).
: "The ubiquitin system." dans: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).
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: "The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome." dans: Molecular biology of the cell, Vol. 18, Issue 2, pp. 569-80, (2007) (PubMed).
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- PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))
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Autre désignation
- Rpn7
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Sujet
- Background: The 26 S proteasome is a protein complex with a molecular mass of 2000 kDa and is highly conserved among eukaryotic organisms. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation. Rpn7 is one of the lid subunits of the 26 S proteasome regulatory particle. The RPN7 gene is known to be essential and required for the integrity of the 26 S complex by establishing a correct lid structure.
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Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
Antigène
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