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PSMD6 anticorps

L’anticorps Lapin Polyclonal anti-PSMD6 a été validé pour WB et IP. Il convient pour détecter PSMD6 dans des échantillons de Saccharomyces cerevisiae. Il y a 4+ publications disponibles.
N° du produit ABIN2452115

Aperçu rapide pour PSMD6 anticorps (ABIN2452115)

Antigène

Voir toutes PSMD6 Anticorps
PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))

Reactivité

  • 50
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  • 27
  • 6
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Saccharomyces cerevisiae

Hôte

  • 48
  • 2
Lapin

Clonalité

  • 49
  • 1
Polyclonal

Conjugué

  • 22
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
Cet anticorp PSMD6 est non-conjugé

Application

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Western Blotting (WB), Immunoprecipitation (IP)
  • Attributs du produit

    Product: Rabbit polyclonal antibody affinity purified with recombinant Rpn7p

    Purification

    Affinity purified

    Immunogène

    Recombinant yeast Rpn7p expressed in E. coli

    Isotype

    IgG
  • Indications d'application

    1) Western blotting: ~1000 fold dilution
    2) Immunoprecipitation Not tested for other applications.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    100 mM NaCl, 10 mM Tris-HCl pH 7.4, 0.05 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    To avoid repeated freezing and thawing, store the antibody solution in aliquots.

    Stock

    -20 °C

    Stockage commentaire

    -20 C. To avoid repeated freezing and thawing, store the antibody solution in aliquots.
  • Isono, Nishihara, Saeki, Yashiroda, Kamata, Ge, Ueda, Kikuchi, Tanaka, Nakano, Toh-e: "The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome." dans: Molecular biology of the cell, Vol. 18, Issue 2, pp. 569-80, (2007) (PubMed).

    Isono, Saeki, Yokosawa, Toh-e: "Rpn7 Is required for the structural integrity of the 26 S proteasome of Saccharomyces cerevisiae." dans: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27168-76, (2004) (PubMed).

    Finley, Tanaka, Mann, Feldmann, Hochstrasser, Vierstra, Johnston, Hampton, Haber, Mccusker, Silver, Frontali, Thorsness, Varshavsky, Byers, Madura, Reed, Wolf, Jentsch, Sommer, Baumeister, Goldberg et al.: "Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. ..." dans: Trends in biochemical sciences, Vol. 23, Issue 7, pp. 244-5, (1998) (PubMed).

    Hershko, Ciechanover: "The ubiquitin system." dans: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).

  • Antigène

    PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))

    Autre désignation

    Rpn7

    Sujet

    Background: The 26 S proteasome is a protein complex with a molecular mass of 2000 kDa and is highly conserved among eukaryotic organisms. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation. Rpn7 is one of the lid subunits of the 26 S proteasome regulatory particle. The RPN7 gene is known to be essential and required for the integrity of the 26 S complex by establishing a correct lid structure.

    Pathways

    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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