PSMD6 anticorps

N° du produit ABIN2452115

Détail du produit anti-PSMD6 anticorps

Antigène: PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))

Reactivité: Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMD6 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Attributs du produit: Product: Rabbit polyclonal antibody affinity purified with recombinant Rpn7p

Purification: Affinity purified

Immunogène: Recombinant yeast Rpn7p expressed in E. coli

Isotype: IgG

Information d'application

Indications d'application: 1) Western blotting: ~1000 fold dilution
2) Immunoprecipitation Not tested for other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 mM NaCl, 10 mM Tris-HCl pH 7.4, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: To avoid repeated freezing and thawing, store the antibody solution in aliquots.

Stock: -20 °C

Stockage commentaire: -20 C. To avoid repeated freezing and thawing, store the antibody solution in aliquots.

Références pour anticorps anti-PSMD6 (ABIN2452115)

Isono, Nishihara, Saeki, Yashiroda, Kamata, Ge, Ueda, Kikuchi, Tanaka, Nakano, Toh-e: "The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome." dans: Molecular biology of the cell, Vol. 18, Issue 2, pp. 569-80, (2007) (PubMed).

Isono, Saeki, Yokosawa, Toh-e: "Rpn7 Is required for the structural integrity of the 26 S proteasome of Saccharomyces cerevisiae." dans: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27168-76, (2004) (PubMed).

Finley, Tanaka, Mann, Feldmann, Hochstrasser, Vierstra, Johnston, Hampton, Haber, Mccusker, Silver, Frontali, Thorsness, Varshavsky, Byers, Madura, Reed, Wolf, Jentsch, Sommer, Baumeister, Goldberg et al.: "Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. ..." dans: Trends in biochemical sciences, Vol. 23, Issue 7, pp. 244-5, (1998) (PubMed).

Hershko, Ciechanover: "The ubiquitin system." dans: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).

Détails sur PSMD6

Antigène: PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))

Autre désignation: Rpn7 (PSMD6 Produits)

Synonymes: anticorps Rpn7, anticorps S10, anticorps SGA-113M, anticorps p42A, anticorps p44S10, anticorps DDBDRAFT_0190867, anticorps DDBDRAFT_0232985, anticorps DDB_0190867, anticorps DDB_0232985, anticorps 2400006A19Rik, anticorps P44s10, anticorps zgc:56471, anticorps p44s10, anticorps rpn7, anticorps s10, anticorps 141231_at, anticorps CG5378, anticorps Dmel\\CG5378, anticorps S10a, anticorps anon-WO0172774.103, anticorps anon-WO0172774.106, anticorps proteasome 26S subunit, non-ATPase 6, anticorps 26S proteasome non-ATPase regulatory subunit 6, anticorps proteasome (prosome, macropain) 26S subunit, non-ATPase, 6, anticorps proteasome 26S subunit, non-ATPase 6 S homeolog, anticorps Regulatory particle non-ATPase 7, anticorps PSMD6, anticorps psmD6, anticorps Psmd6, anticorps psmd6, anticorps psmd6.S, anticorps Rpn7, anticorps rpn-7

Sujet: Background: The 26 S proteasome is a protein complex with a molecular mass of 2000 kDa and is highly conserved among eukaryotic organisms. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation. Rpn7 is one of the lid subunits of the 26 S proteasome regulatory particle. The RPN7 gene is known to be essential and required for the integrity of the 26 S complex by establishing a correct lid structure.

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway