RRM2 anticorps (C-Term)

N° du produit ABIN2452118

Il existe 1 publication pour ce produit. L’anticorps anti-RRM2 Polyclonal Lapin est utilisé pour la détection de RRM2 dans des échantillons de Humain, Souris, Rat et Xenopus laevis. Il a été validé pour WB et IF.

Aperçu rapide pour RRM2 anticorps (C-Term) (ABIN2452118)

Antigène: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Reactivité: Humain, Souris, Rat, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRM2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-RRM2 anticorps

Épitope: C-Term

Réactivité croisée (Details): Not tested in other species.

Purification: Affinity-purified with the immunogen peptide

Stérilité: Sterile filtered

Immunogène: C-terminal peptide of Human and Mouse RRM2, C-TENSFTLDADF, conjugated with KLH

Information d'application

Indications d'application: 1) Western blotting: ~ 1/1,000 dilution
Not tested for other applications

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS (x1), 50 % glycerol. Azide and carrier free.

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Upon receipt aliquot and store at -20 C

Références pour anticorps anti-RRM2 (ABIN2452118)

Takada, Shibata, Hiraoka, Masuda: "Identification of ribonucleotide reductase protein R1 as an activator of microtubule nucleation in Xenopus egg mitotic extracts." dans: Molecular biology of the cell, Vol. 11, Issue 12, pp. 4173-87, (2000) (PubMed).

Détails sur RRM2

Antigène: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Autre désignation: RRM2 / RNR-R2

Sujet: Betag Ribonucleoside-diphosphate reductase subunit M2 (RRM2, 389 aa, 45 kDa) also known as ribonucleotide reductase subunit R2 (RNR-R2), is a rate-limiting subunit of an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides. Deoxyribonucleotides in turn are used in the synthesis of DNA. The reaction catalyzed by RNR is strictly conserved in all living organisms. Furthermore RNR plays a critical role in regulating the total rate of DNA synthesis so that DNA to cell mass is maintained at a constant ratio during cell division and DNA repair.

UniProt: P31350

Pathways: Mitotic G1-G1/S Phases