PCDHA12 anticorps

N° du produit ABIN2459278

Cet anticorps Lapin Polyclonal détecte spécifiquement PCDHA12 dans WB et ELISA. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour PCDHA12 anticorps (ABIN2459278)

Antigène: PCDHA12 (Protocadherin alpha 12 (PCDHA12))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHA12 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PCDHA12 anticorps

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDHA12.

Information d'application

Indications d'application: PCDHA12 antibody can be used for detection of PCDHA12 by ELISA at 1:312500. PCDHA12 antibody can be used for detection of PCDHA12 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCDHA12 antibody at -20 °C.

Détails sur PCDHA12

Antigène: PCDHA12 (Protocadherin alpha 12 (PCDHA12))

Autre désignation: PCDHA12

Sujet: PCDHA12 is a potential calcium-dependent cell-adhesion protein. PCDHA12 may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Poids moléculaire: 99 kDa

ID gène: 56137

NCBI Accession: NP_061726

UniProt: Q9UN75