TRIB2 anticorps

N° du produit ABIN2459888

Détail du produit anti-TRIB2 anticorps

Antigène: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIB2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIB2.

Information d'application

Indications d'application: TRIB2 antibody can be used for detection of TRIB2 by ELISA at 1:312500. TRIB2 antibody can be used for detection of TRIB2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TRIB2 antibody at -20 °C.

Détails sur TRIB2

Antigène: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Autre désignation: TRIB2 (TRIB2 Produits)

Synonymes: anticorps TRIB2, anticorps Trb2, anticorps Xtrbl, anticorps gs3955, anticorps c5fw, anticorps trb2, anticorps xtrb2, anticorps TRB2, anticorps C5FW, anticorps GS3955, anticorps TRB-2, anticorps AW319517, anticorps RGD1564451, anticorps tribbles pseudokinase 2, anticorps tribbles pseudokinase 2 S homeolog, anticorps TRIB2, anticorps trib2, anticorps trib2.S, anticorps Trib2

Sujet: TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia.

Poids moléculaire: 39 kDa

ID gène: 28951

NCBI Accession: NP_067675

UniProt: Q92519