COX18 anticorps

N° du produit ABIN2459950

Détail du produit anti-COX18 anticorps

Antigène: COX18 (Cytochrome C Oxidase Assembly Homolog 18 (COX18))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COX18 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COX18.

Information d'application

Indications d'application: COX18 antibody can be used for detection of COX18 by ELISA at 1:1562500. COX18 antibody can be used for detection of COX18 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store COX18 antibody at -20 °C.

Détails sur COX18

Antigène: COX18 (Cytochrome C Oxidase Assembly Homolog 18 (COX18))

Autre désignation: COX18 (COX18 Produits)

Synonymes: anticorps COX18HS, anticorps BC038311, anticorps RGD1559547, anticorps COX18 cytochrome c oxidase assembly factor L homeolog, anticorps COX18, cytochrome c oxidase assembly factor, anticorps cytochrome c oxidase assembly protein 18, anticorps cox18.L, anticorps COX18, anticorps Cox18

Sujet: COX18 is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. COX18 is essential for the activity and assembly of cytochrome c oxidase. COX18 plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2, MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).

Poids moléculaire: 37 kDa

ID gène: 285521

NCBI Accession: NP_776188

UniProt: Q8N8Q8