RACGAP1 anticorps
Aperçu rapide pour RACGAP1 anticorps (ABIN2460314)
Antigène
Voir toutes RACGAP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Antibody is purified by protein A chromatography method.
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Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RACGAP1.
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Indications d'application
- RACGAP1 antibody can be used for detection of RACGAP1 by ELISA at 1:1562500. RACGAP1 antibody can be used for detection of RACGAP1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Concentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store RACGAP1 antibody at -20 °C.
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- RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))
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Autre désignation
- RACGAP1
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Sujet
- Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC, and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
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Poids moléculaire
- 71 kDa
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ID gène
- 29127
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NCBI Accession
- NP_037409
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UniProt
- Q9H0H5
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Pathways
- Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor
Antigène
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