NCOR1 anticorps

N° du produit ABIN2460482

Détail du produit anti-NCOR1 anticorps

Antigène: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Reactivité: Humain, Souris, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOR1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NCOR1.

Information d'application

Indications d'application: NCOR1 antibody can be used for detection of NCOR1 by ELISA at 1:62500. NCOR1 antibody can be used for detection of NCOR1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NCOR1 antibody at -20 °C.

Détails sur NCOR1

Antigène: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Autre désignation: NCOR1 (NCOR1 Produits)

Synonymes: anticorps ncor, anticorps zgc:56355, anticorps 5730405M06Rik, anticorps A230020K14Rik, anticorps N-CoR, anticorps RIP13, anticorps Rxrip13, anticorps mKIAA1047, anticorps N-CoR1, anticorps TRAC1, anticorps hN-CoR, anticorps nuclear receptor corepressor 1, anticorps nuclear receptor co-repressor 1, anticorps nuclear receptor corepressor 1 pseudogene, anticorps nuclear receptor corepressor 1 S homeolog, anticorps ncor1, anticorps NCOR1, anticorps CpipJ_CPIJ002507, anticorps LOC100343278, anticorps Ncor1, anticorps ncor1.S

Sujet: NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.

Poids moléculaire: 104 kDa

ID gène: 9611

UniProt: Q86YY0

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process