POU4F3 anticorps

N° du produit ABIN2460646

Cet anticorps Lapin Polyclonal détecte spécifiquement POU4F3 dans WB, ELISA et IHC. Il présente une réactivité envers Humain, Souris, Rat, Chien et Poisson zèbre (Danio rerio).

Aperçu rapide pour POU4F3 anticorps (ABIN2460646)

Antigène: POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POU4F3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-POU4F3 anticorps

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POU4F3.

Information d'application

Indications d'application: POU4F3 antibody can be used for detection of POU4F3 by ELISA at 1:312500. POU4F3 antibody can be used for detection of POU4F3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store POU4F3 antibody at -20 °C.

Détails sur POU4F3

Antigène: POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))

Autre désignation: POU4F3

Sujet: POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.

Poids moléculaire: 37 kDa

ID gène: 5459

NCBI Accession: NP_002691

UniProt: Q15319

Pathways: Sensory Perception of Sound