POU4F3 anticorps

N° du produit ABIN2460646

Détail du produit anti-POU4F3 anticorps

Antigène: POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POU4F3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POU4F3.

Information d'application

Indications d'application: POU4F3 antibody can be used for detection of POU4F3 by ELISA at 1:312500. POU4F3 antibody can be used for detection of POU4F3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store POU4F3 antibody at -20 °C.

Détails sur POU4F3

Antigène: POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))

Autre désignation: POU4F3 (POU4F3 Produits)

Synonymes: anticorps POU4F3, anticorps BRN-3, anticorps BRN3, anticorps BRN3C, anticorps DFNA15, anticorps BRN-3.1, anticorps brn-3c, anticorps brn3.1, anticorps brn3c, anticorps Brn3.1, anticorps Brn3c, anticorps ddl, anticorps dreidel, anticorps POU class 4 homeobox 3, anticorps POU domain, class 4, transcription factor 3, anticorps POU4F3, anticorps Pou4f3, anticorps pou4f3

Sujet: POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.

Poids moléculaire: 37 kDa

ID gène: 5459

NCBI Accession: NP_002691

UniProt: Q15319

Pathways: Sensory Perception of Sound