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Claudin 11 anticorps

Cet anticorps anti-Claudin 11 est un anticorps Lapin Polyclonal détectant Claudin 11 dans WB, ELISA et IHC. Adapté pour Humain et Chien.
N° du produit ABIN2460771

Aperçu rapide pour Claudin 11 anticorps (ABIN2460771)

Antigène

Voir toutes Claudin 11 (CLDN11) Anticorps
Claudin 11 (CLDN11)

Reactivité

  • 25
  • 25
  • 25
  • 20
  • 15
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Chien

Hôte

  • 39
  • 1
Lapin

Clonalité

  • 38
  • 2
Polyclonal

Conjugué

  • 23
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Claudin 11 est non-conjugé

Application

  • 35
  • 14
  • 13
  • 13
  • 11
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Purification

    Antibody is purified by peptide affinity chromatography method.

    Immunogène

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLDN11.
  • Indications d'application

    CLDN11 antibody can be used for detection of CLDN11 by ELISA at 1:312500. CLDN11 antibody can be used for detection of CLDN11 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    Concentration

    1 mg/mL

    Buffer

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    Conseil sur la manipulation

    As with any antibody avoid repeat freeze-thaw cycles.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store CLDN11 antibody at -20 °C.
  • Antigène

    Claudin 11 (CLDN11)

    Autre désignation

    CLDN11

    Sujet

    CLDN11 belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.

    Poids moléculaire

    22 kDa

    ID gène

    5010

    NCBI Accession

    NP_005593

    UniProt

    O75508

    Pathways

    Hepatitis C
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