ATP7A anticorps

N° du produit ABIN2460808

Cet anticorps Lapin Polyclonal détecte spécifiquement ATP7A dans WB et ELISA. Il présente une réactivité envers Humain et Chien.

Aperçu rapide pour ATP7A anticorps (ABIN2460808)

Antigène: ATP7A (ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP7A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ATP7A anticorps

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATP7A.

Information d'application

Indications d'application: ATP7A antibody can be used for detection of ATP7A by ELISA at 1:1562500. ATP7A antibody can be used for detection of ATP7A by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATP7A antibody at -20 °C.

Détails sur ATP7A

Antigène: ATP7A (ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))

Autre désignation: ATP7A

Sujet: The ATP7A gene encodes the Menkes copper-translocating P-type ATPase, a ubiquitous protein that regulates the absorption of copper in the gastrointestinal tract. Inside cells, this protein has a dual function: it delivers copper to cuproenzymes in the Golgi compartment and effluxes excess copper. The trafficking mechanism and catalytic activity combine to facilitate absorption and intercellular transport of copper. Menkes disease, a systemic copper deficiency disorder, is caused by mutations in the ATP7A gene.

Poids moléculaire: 30 kDa, 163 kDa, 70 kDa

ID gène: 538

UniProt: Q762B6

Pathways: Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process