MED17 anticorps

N° du produit ABIN2460890

Détail du produit anti-MED17 anticorps

Antigène: MED17 (Mediator Complex Subunit 17 (MED17))

Reactivité: Humain, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED17 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CRSP6.

Information d'application

Indications d'application: CRSP6 antibody can be used for detection of CRSP6 by ELISA at 1:12500. CRSP6 antibody can be used for detection of CRSP6 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CRSP6 antibody at -20 °C.

Détails sur MED17

Antigène: MED17 (Mediator Complex Subunit 17 (MED17))

Autre désignation: CRSP6 (MED17 Produits)

Synonymes: anticorps crsp6, anticorps CRSP6, anticorps CRSP77, anticorps DRIP80, anticorps TRAP80, anticorps 77kDa, anticorps C330002H14Rik, anticorps Crsp6, anticorps Trap80, anticorps mediator of RNA polymerase II transcription subunit 17, anticorps mediator complex subunit 17, anticorps mediator complex subunit 17 L homeolog, anticorps AOR_1_2446154, anticorps VDBG_01663, anticorps med17, anticorps med17.L, anticorps MED17, anticorps Med17

Sujet: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor- (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

Poids moléculaire: 73 kDa

ID gène: 9440

NCBI Accession: NP_004259

UniProt: Q9NVC6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha