P2RX1 anticorps

N° du produit ABIN2461101

Détail du produit anti-P2RX1 anticorps

Antigène: P2RX1 (Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1))

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P2RX1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human P2RX1.

Information d'application

Indications d'application: P2RX1 antibody can be used for detection of P2RX1 by ELISA at 1:312500. P2RX1 antibody can be used for detection of P2RX1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store P2RX1 antibody at -20 °C.

Détails sur P2RX1

Antigène: P2RX1 (Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1))

Autre désignation: P2RX1 (P2RX1 Produits)

Synonymes: anticorps p2xr1, anticorps P2X1, anticorps AI323649, anticorps BB122383, anticorps P2x, anticorps Pdcd3, anticorps RP-2, anticorps P2XMR, anticorps P2X1R, anticorps purinergic receptor P2X, ligand-gated ion channel, 1, anticorps purinergic receptor P2X 1, anticorps calcium/calmodulin dependent protein kinase kinase 1, anticorps p2rx1, anticorps P2RX1, anticorps P2rx1, anticorps CAMKK1

Sujet: P2RX1 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.

Poids moléculaire: 45 kDa

ID gène: 5023

NCBI Accession: NP_002549

UniProt: P51575

Pathways: Positive Regulation of Endopeptidase Activity