GJB2 anticorps

N° du produit ABIN2461384

Cet anticorps Lapin Polyclonal détecte spécifiquement GJB2 dans WB et ELISA. Il présente une réactivité envers Humain et Chien.

Aperçu rapide pour GJB2 anticorps (ABIN2461384)

Antigène: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GJB2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GJB2 anticorps

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GJB2.

Information d'application

Indications d'application: GJB2 antibody can be used for detection of GJB2 by ELISA at 1:62500. GJB2 antibody can be used for detection of GJB2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GJB2 antibody at -20 °C.

Détails sur GJB2

Antigène: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Autre désignation: GJB2

Sujet: Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 (MIM 121014) is designated alpha-1 gap junction protein, whereas CX32 (GJB1, MIM 304040) and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43.

Poids moléculaire: 25 kDa

ID gène: 2706

NCBI Accession: NP_003995

UniProt: P29033

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization