TIMELESS anticorps

N° du produit ABIN2461712

Détail du produit anti-TIMELESS anticorps

Antigène: TIMELESS (Timeless Homolog (TIMELESS))

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMELESS est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TIMELESS.

Information d'application

Indications d'application: TIMELESS antibody can be used for detection of TIMELESS by ELISA at 1:312500. TIMELESS antibody can be used for detection of TIMELESS by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TIMELESS antibody at -20 °C.

Détails sur TIMELESS

Antigène: TIMELESS (Timeless Homolog (TIMELESS))

Autre désignation: TIMELESS (TIMELESS Produits)

Synonymes: anticorps TIM, anticorps TIM1, anticorps hTIM, anticorps C77407, anticorps Debt69, anticorps tim, anticorps CG3234, anticorps Dmel\\CG3234, anticorps Ritsu, anticorps Tim, anticorps dTIM, anticorps dTim, anticorps dtim, anticorps mel_tim, anticorps rit, anticorps tim1, anticorps XTimeless1, anticorps timeless, anticorps timelessb, anticorps TIMELESS, anticorps MXC20.14, anticorps MXC20_14, anticorps htim, anticorps im:6903167, anticorps wu:fa95g04, anticorps wu:fd23d07, anticorps timeless circadian regulator, anticorps timeless circadian clock 1, anticorps timeless, anticorps timeless circadian clock, anticorps timeless circadian clock S homeolog, anticorps timeless family protein, anticorps TIMELESS, anticorps Timeless, anticorps tim, anticorps timeless.S, anticorps Tim, anticorps ATIM, anticorps timeless, anticorps LOC100328917

Sujet: The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.

Poids moléculaire: 139 kDa

ID gène: 8914

NCBI Accession: NP_003911

UniProt: Q9UNS1

Pathways: Protein targeting to Nucleus, Photoperiodism