DMAP1 anticorps

N° du produit ABIN2461898

Détail du produit anti-DMAP1 anticorps

Antigène: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMAP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DMAP1.

Information d'application

Indications d'application: DMAP1 antibody can be used for detection of DMAP1 by ELISA at 1:1562500. DMAP1 antibody can be used for detection of DMAP1 by western blot at 5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DMAP1 antibody at -20 °C.

Détails sur DMAP1

Antigène: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Autre désignation: DMAP1 (DMAP1 Produits)

Synonymes: anticorps Afu4g07380, anticorps T8I13.5, anticorps DNMAP1, anticorps DNMTAP1, anticorps EAF2, anticorps MEAF2, anticorps SWC4, anticorps zgc:55593, anticorps dnmap1, anticorps dnmtap1, anticorps eaf2, anticorps meaf2, anticorps swc4, anticorps 1500016M21Rik, anticorps Dmtap1, anticorps mKIAA1425, anticorps DNA methyltransferase 1-associated protein DMAP1, anticorps DNA methyltransferase 1-associated protein 1, anticorps DNA methyltransferase 1 associated protein 1, anticorps myb-like transcription factor family protein, anticorps DNA methyltransferase 1 associated protein 1 L homeolog, anticorps AFUA_4G07380, anticorps NFIA_108840, anticorps ACLA_046700, anticorps CpipJ_CPIJ017959, anticorps Bm1_47540, anticorps PMAA_026820, anticorps AFLA_112450, anticorps TSTA_072020, anticorps BDBG_02603, anticorps AT2G47210, anticorps CpipJ_CPIJ007438, anticorps DMAP1, anticorps dmap1, anticorps dmap1.L, anticorps Dmap1

Sujet: DMAP1 is a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

Poids moléculaire: 53 kDa

ID gène: 55929

NCBI Accession: NP_061973

UniProt: Q9NPF5