ALAD anticorps

N° du produit ABIN2462445

Cet anticorps anti-ALAD est un anticorps Lapin Polyclonal détectant ALAD dans WB et ELISA. Adapté pour Humain et Chien.

Aperçu rapide pour ALAD anticorps (ABIN2462445)

Antigène: ALAD (Aminolevulinate Dehydratase (ALAD))

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALAD est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ALAD anticorps

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ALAD.

Information d'application

Indications d'application: ALAD antibody can be used for detection of ALAD by ELISA at 1:312500. ALAD antibody can be used for detection of ALAD by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ALAD antibody at -20 °C.

Détails sur ALAD

Antigène: ALAD (Aminolevulinate Dehydratase (ALAD))

Autre désignation: ALAD

Sujet: The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 Molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 Molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: 39 kDa, 37 kDa

ID gène: 210

NCBI Accession: NP_001003945

UniProt: Q6ZMU0