SLC26A5 anticorps

N° du produit ABIN2462788

Cet anticorps Lapin Polyclonal détecte spécifiquement SLC26A5 dans WB, ELISA et IHC. Il présente une réactivité envers Humain, Souris, Rat et Chien.

Aperçu rapide pour SLC26A5 anticorps (ABIN2462788)

Antigène: SLC26A5 (Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC26A5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SLC26A5 anticorps

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC26A5.

Information d'application

Indications d'application: SLC26A5 antibody can be used for detection of SLC26A5 by ELISA at 1:312500. SLC26A5 antibody can be used for detection of SLC26A5 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SLC26A5 antibody at -20 °C.

Détails sur SLC26A5

Antigène: SLC26A5 (Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5))

Autre désignation: SLC26A5

Sujet: SLC26A5 is a member of the SLC26A/SulP transporter family. SLC26A5 is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in its gene have been associated with non-syndromic hearing loss.This gene is a member of the SLC26A/SulP transporter family. It encodes a protein that is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in this gene have been associated with non-syndromic hearing loss. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Poids moléculaire: 81 kDa, 75 kDa, 56 kDa

ID gène: 375611

NCBI Accession: NP_945350

UniProt: P58743

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport