RFC3 anticorps

N° du produit ABIN2462934

Cet anticorps anti-RFC3 est un anticorps Lapin Polyclonal détectant RFC3 dans WB et ELISA. Adapté pour Humain et Chien.

Aperçu rapide pour RFC3 anticorps (ABIN2462934)

Antigène: RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFC3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RFC3 anticorps

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RFC3.

Information d'application

Indications d'application: RFC3 antibody can be used for detection of RFC3 by ELISA at 1:62500. RFC3 antibody can be used for detection of RFC3 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RFC3 antibody at -20 °C.

Détails sur RFC3

Antigène: RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))

Autre désignation: RFC3

Sujet: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. RFC3 is the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits.The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 38 kD subunit. This subunit is essential for the interaction between the 140 kD subunit and the core complex that consists of the 36, 37, and 40 kD subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Poids moléculaire: 40 kDa

ID gène: 5983

NCBI Accession: NP_002906

UniProt: P40938

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA