SEC63 anticorps

N° du produit ABIN2463021

Cet anticorps anti-SEC63 est un anticorps Lapin Polyclonal détectant SEC63 dans WB et ELISA. Adapté pour Humain, Souris et Chien.

Aperçu rapide pour SEC63 anticorps (ABIN2463021)

Antigène: SEC63 (SEC63 Homolog (SEC63))

Reactivité: Humain, Souris, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEC63 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SEC63 anticorps

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SEC63.

Information d'application

Indications d'application: SEC63 antibody can be used for detection of SEC63 by ELISA at 1:62500. SEC63 antibody can be used for detection of SEC63 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SEC63 antibody at -20 °C.

Détails sur SEC63

Antigène: SEC63 (SEC63 Homolog (SEC63))

Autre désignation: SEC63

Sujet: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. SEC63 is an integral membrane protein located in the rough ER.The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

Poids moléculaire: 88 kDa

ID gène: 11231

NCBI Accession: NP_009145

UniProt: Q9UGP8

Pathways: ER-Nucleus Signaling