SEC63 anticorps
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- Antigène Voir toutes SEC63 Anticorps
- SEC63 (SEC63 Homolog (SEC63))
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Reactivité
- Humain, Souris, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SEC63 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SEC63.
- Top Product
- Discover our top product SEC63 Anticorps primaire
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- Indications d'application
- SEC63 antibody can be used for detection of SEC63 by ELISA at 1:62500. SEC63 antibody can be used for detection of SEC63 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SEC63 antibody at -20 °C.
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- Antigène
- SEC63 (SEC63 Homolog (SEC63))
- Autre désignation
- SEC63 (SEC63 Produits)
- Synonymes
- anticorps DNAJC23, anticorps ERdj2, anticorps PRO2507, anticorps SEC63L, anticorps 5730478J10Rik, anticorps AI649014, anticorps AW319215, anticorps SEC63-like, anticorps zgc:92718, anticorps SEC63 homolog, protein translocation regulator, anticorps SEC63-like (S. cerevisiae), anticorps SEC63 homolog, protein translocation regulator L homeolog, anticorps SEC63, anticorps Sec63, anticorps sec63, anticorps sec63.L
- Sujet
- The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. SEC63 is an integral membrane protein located in the rough ER.The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
- Poids moléculaire
- 88 kDa
- ID gène
- 11231
- NCBI Accession
- NP_009145
- UniProt
- Q9UGP8
- Pathways
- ER-Nucleus Signaling
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