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HS3ST5 anticorps

HS3ST5 Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2463259
  • Antigène Voir toutes HS3ST5 Anticorps
    HS3ST5 (Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 5 (HS3ST5))
    Reactivité
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 3
    Lapin
    Clonalité
    • 3
    Polyclonal
    Conjugué
    • 3
    Cet anticorp HS3ST5 est non-conjugé
    Application
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by peptide affinity chromatography method.
    Immunogène
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HS3ST5.
    Top Product
    Discover our top product HS3ST5 Anticorps primaire
  • Indications d'application
    HS3ST5 antibody can be used for detection of HS3ST5 by ELISA at 1:1562500. HS3ST5 antibody can be used for detection of HS3ST5 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Conseil sur la manipulation
    As with any antibody avoid repeat freeze-thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store HS3ST5 antibody at -20 °C.
  • Antigène
    HS3ST5 (Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 5 (HS3ST5))
    Autre désignation
    HS3ST5 (HS3ST5 Produits)
    Synonymes
    anticorps 3-OST-5, anticorps 3OST5, anticorps HS3OST5, anticorps NBLA04021, anticorps D930005L05Rik, anticorps Gm1151, anticorps Hs3ost5, anticorps HS3ST6, anticorps HS3ST5, anticorps heparan sulfate-glucosamine 3-sulfotransferase 5, anticorps heparan sulfate (glucosamine) 3-O-sulfotransferase 5, anticorps HS3ST5, anticorps Hs3st5, anticorps hs3st5
    Sujet
    HS3ST5 is the rate limiting enzyme for synthesis of HSact. It performs the crucial step modification in the biosynthesis of anticoagulant heparan sulfate (HSact) that is to complete the structure of the antithrombin pentasaccharide binding site. HS3ST5 also generates GlcUA-GlcNS or IdoUA-GlcNS and IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry.HS3ST5 belongs to a group of heparan sulfate 3-O-sulfotransferases (EC 2.8.2.23) that transfer sulfate from 3-prime-phosphoadenosine 5-prime phosphosulfate (PAPS) to heparan sulfate and heparin (Mochizuki et al., 2003 [PubMed 12740361]).
    Poids moléculaire
    40 kDa
    ID gène
    222537
    NCBI Accession
    NP_705840
    UniProt
    Q8IZT8
    Pathways
    Glycosaminoglycan Metabolic Process
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